Medical Biology \ 1-1
Mehmet Topaktaş Genetics is the science that studies heredity and heredity in living things. In the science of genetics, besides the classic subjects such as Mendel's Studies, there are also rapidly changing fields, such as in the field of Molecular Genetics. The main thing in a genetics book is to provide the latest information in rapidly changing fields along with classical subjects. In addition, the author should reflect his own views on the book after synthesizing the acquired knowledge. For these reasons, I wanted this book to include not only the topics that I teach my students during limited class hours, but also all the basic topics that should be in a genetics book. That's what I tried to do while writing this book. For this reason, it took many years to write the book, and as a result, this work emerged. I hope that my book will add new richness to the knowledge of the target audience.
Target audience for this book:
• Scientists working in the field of genetics,
• Research assistants working on a postgraduate thesis in the field of genetics and students working on a postgraduate thesis,
• Students of the Biology, Molecular Biology and Genetics Departments of the Faculties of Science and Letters, the Science and Biology Teaching departments of the Faculties of Agriculture, Medicine, Dentistry, Veterinary Faculties, Education Faculties,
• Biology teachers of high schools and science teachers of primary schools and
• People from all walks of life who are interested in genetics.
The fact that the book reaches its goal will make me forget all my tiredness.
Ayşe Çakır Gündoğdu, Canan Eroğlu Güneş, Cansu Özbayer, Cansu Özbayer, Cemile Merve Seymen, Ceyda Çolakoğlu, Ceyhan Hacıoğlu, Ecir Ali Çakmak, Emine Yağcı, Emrah Tümer, Ercan Kurar, Ertan Kanbur, Ezgi Kar, Faruk Saydam, Fatih Kar, Gamze Güney Eskiler, Gülşah Çeçener, Hülyam Kurt, Işıl Ezgi Eryılmaz, İrfan Değirmenci, Mahmut Özdemir, Merve Deniz Değirmenci, Miriş Dikmen, Muammer Yılmaz, Neslihan Meriç, Özlem Sağlam Uçar, Rumeysa Özyurt, Sinan Değirmenci, Ünal Egeli With the acceptance of cancer as a genetic disease, scientists continue to research cancer in genetic and molecular terms. Clarifying the molecular mechanisms of cell division and proliferation and learning the molecular pathways in the cell indicate that more research is needed on molecular structures to be targeted in cancer therapy.
We hope that the book "Cancer Genetics and Molecular Biology" will be a useful resource containing up-to-date information that will benefit scientists who will do research in this field and our students studying in departments such as Medicine, Molecular Biology and Genetics, Biology, Biochemistry, Pharmacy and Veterinary.
In the book, cancer epidemiology, carcinogenesis, molecular targets and signaling pathways in cancer, cancer genetics and cytogenetics, genes responsible for cancer, the relationship between cellular aging and cancer, cell death mechanisms and cancer, characteristics of cancer cells, cancer types, angiogenesis, metastasis, immunity, plasticity, topics such as cancer stem cells, biomarkers, ion channels and cancer relationship and multi-drug resistance in cancer are discussed.
Adeviye Elçi Atılgan, Ahmet Cihat Genc, Ahmet Gökçe, Ahmet Hakan Erbil, Ahmet Tarık Eminler, Ahmet Uygun, Ali Arslan, Alpaslan Tanoğlu, Anıl Erdik, Arife Derda Yücel Şen, Aybala Neslihan Alagöz, Aycan Gündoğdu, Aysun Kaya, Ayşe Betül Şahin, Ayşe Caner, Ayşe Erdoğan, Ayşegül Pala, Bahar Sevimli Dikicier, Barış Otlu, Berkay Yekta Ekreç, Bilal Toka, Bora Doğan, Ceyhun Varım, Demet Teker Düztaş, Dilara Carı Güngör, Doğukan Yılmaz, Duygu Ağagündüz, Duygu Sağlam, Ece Öneş, Efsun Karabudak, Elif Özözen Şahin, Elmas Pınar Kahraman Kılbaş, Emel Uzunoğlu, Emre Uzun, Esra Yazıcı, Fahri Ovalı, Fatih Gültekin, Fatma Cevahir, Ferhat G. Aslan, Feride Ayyıldız, Ferzan Arslan, Gamze Akbulut, Gamze Gürsoy, Gökhan Güngör, Gülfem Terek Ece, Gülsüm Kaya, Hacı İbrahim Çimen, Hakan Alagözlü, Hande Toptan, Hasan Basri Savaş, Hasan Salih Sağlam, Hatice Bölükbaşı, Hilal Uslu Yuvacı, Hilal Yıldıran, Isa Yuvacı, Işkın Pınar Zarakolu, İbrahim Halil Miraloğlu, İbrahim Tekeoğlu, İlhan Hacıbekiroğlu, İpek Mumcuoğlu, İshak Özel Tekin, K. Esen Karaca Çelik, Kerem Yılmaz, Kurtuluş Buruk, Kübra Özata Gündoğdu, Kürşat Bora Çarman, Manolya Eser Öner, Mehmet Bülent Vatan, Mehmet Köroğlu, Meltem Yalınay, Mendane Saka, Merve Pilavcı Adıgül, Muhammed Ayaz, Murat Baş, Murat Baş, Murat Kekilli, Mustafa Altındiş, Nergis Ekmen, Neslihan Yeşilyurt, Nuray Bozkurt, Nursan Çınar, Ödül Eğritaş Gürkan, Öner Özdemir, Özge Küçükerdönmez, Özkan Ufuk Nalbantoğlu, Özlem Koyuncu Özyurt, Pelin Eşme, Perihan Varım, Pınar Onat, Rabiye Güney, Rana Nagihan Akder, Saniye Bilici, Saniye Sözlü, Selma Altındiş, Sema Aşkın Keçeli, Semra Öz, Sena Genç Elden, Serap Süzük, Sevinç Yücecan, Sümeyye Akın, Şefik Şanal Alkan, Taner Akyol, Tarkan Karakan, Tuba Dal, Uğur Sezerman, Ümit Yasemin Sert, Yağmur Yeşilyurt, Yasemin Çakır-Gökkurt, Yasemin Ertaş Öztürk, Yusuf Aydemir, Yusuf Yakupoğulları, Zeynep Cansu Çalışkan In this book, which aims to bring together the secrets of healthy life and related researches of the future in a comprehensive and encyclopedic way, almost all the issues related to the microbiota in the clinic are mentioned. In addition, information on probiotics and the use of probiotics in clinical spectra is presented in their latest updated versions, while different application areas of probiotics and rational nutrition are listed one after the other.
Although the effects of microbiota and probiotics on health and diseases are known, there are still many questions to be answered. Although studies on microbiota have been started in Turkey, infrastructure and standardization problems have not been resolved and there is a need for regulation in many aspects. Because this area has a strategic importance for our country. Although it is changing rapidly, our eating habits are still different from Western countries. Therefore, it is likely that we have a unique intestinal bacterial structure of our own. With the studies to be done on this subject, special diagnosis and treatment methods can be developed for us. The Microbiota, Probiotics and Rational Nutrition book, in which the latest information, experiences and the point reached are discussed by teachers working in different fields of expertise, will also be instrumental in sharing and planning on what can be done in Turkey, who will take part in what way, and how to work.
With the hope and hope that it will be useful to all its readers...
Behiç Serpek The Organic Chemistry book, which was mainly prepared to be useful to students in biology-based faculties such as Medicine, Veterinary Medicine, Dentistry and Pharmacy, consists of two parts, Basic and Organic Chemistry. The first chapter starts with the structure of atoms, which are the smallest building blocks that show all the qualities of an element, and covers chemical bonds, acids and bases, important physicochemical principles, and thermodynamics with analytical methods.
In the second part, the basic principles of organic chemistry, also defined as C-Chemistry, isomer, biologically important organic substance groups and reactions specific to these groups, monomers such as amino acids and monosaccharides in the structure of living things, polymers such as proteins, polysaccharides and nucleic acids are important biochemically. molecular structures have been tried to be given briefly and concisely.
It is thought that the book, which tries to emphasize the biological and biochemical importance of the subjects prepared in color so that the changes in the molecular structures during chemical reactions can be seen more clearly and the shapes can be observed more easily, will contribute to the education in the faculties that provide biology-based education and close the gap on this subject.
Ayça Taş, Ebru Derelli Tüfekçi, Ertan Mahir Korkmaz, Gülşen Güçlü, Hasan Hüseyin Başıbüyük, Mahir Budak, Mehmet Gülmez, Melissa Şafak Salman, Özgül Doğan, Sebahattin Karabulut, Serhat Bozkurt, Serhat Sirekbasan, Sevda Hastaoğlu Örgen, Songül Ulusoy, Tuğba Gürkök Tan, Zeynep Deniz Şahin İnan The development of medical biology and genetics with each passing day contributes to the development of new diagnostic and treatment methods in medicine. This book is a versatile book in which basic and up-to-date information is compiled in the field of medical biology and genetics and the acquisition of knowledge in this field is comprehensively covered. It also provides a framework for students to understand the field of medical biology and genetics, while providing the basis for establishing a continuing education program in this field.
Medical Biology and Genetics for Health Professionals book; I hope it will be a resource for everyone interested in medicine and biology education and will motivate them to take a stronger step towards science and new ideas...
Ayşegül Sarpkaya, Ceyda Okudu, Demet Taşdemir Kahraman, Ebru Temiz, Esra Bozgeyik, İbrahim Bozgeyik, Reşat Dikme Click to download PDF file


Medical biology and genetics is the science of biology that studies the hereditary character that affects human existence and health. This book has been arranged according to the needs of the departments to be used during the conduct of the "Medical Biology and Genetics" course taught in the first years of Health Services programs and faculties. The selected course contents are handled in a general framework and aim to provide students with a basic perspective on the field. The chapters of the book are planned as seven chapters in accordance with this purpose. In the first three chapters, cell biology and metabolism are explained from simple to complex in the light of current literature. In the following three chapters, the structure and organization of hereditary material are explained and detailed information is given about genetic diseases affecting human health. In the last section, cancer genetics and pathogenesis are explained and the pathophysiological process from gene to cell behavior is discussed as a whole.
Students who are new to higher education have difficulty in understanding the main subjects of medical biology and genetics, which consist of abstract data. For this reason, the topics in the book are explained in an understandable language as well as being embodied with detailed drawings. Although the topics are explained briefly and concisely, they are supported by the current literature.
Diler Aslan Medical (clinical) laboratory management has a key position in the healthcare sector in terms of human health, patient safety, quality of community/population life and cost effective healthcare expenditures. Medical/Clinical laboratories (MLs/CLs) are also the data centers of healthcare institutions. Laboratory tests are requested from approximately 80% of individuals admitted to a health institution, and 70-80% of medical decisions are made based on the test results. In addition to providing reliable test results to each individual/patient in a timely and cost-effective manner, information about public health status can also be obtained from laboratory data.
Their success in these responsibilities and duties is directly proportional to their ability to
establish a well-structured risk, quality and process-based system.
In this book: a risk, quality and process-based management model is presented. The book covers the steps of recognizing and introducing the process framework of a medical (clinical) laboratory that is composed of the management and support processes. The total examination process, which is the main core process of an ML/CL, is composed of 5 subprocesses. The steps also include the application of risk and quality management to every process. By following this book, the laboratory professional will be able to define and introduce all the processes of a ML/CL and establish the management system with the process approach. Laboratory professionals will be able to familiarize themselves with each process and create process-oriented risk and quality management systems following the recommended steps. A continuous process improvement system, based on the Plan-Do-Check-Act (PDCA) Cycle, will also be established. Hence, the ML/CL will be prepared to meet all the requirements of external assessment programs, including the ISO 9001:2015 Quality Management System Standard, the excellence models such as the EFQM, and the Accreditation Standard ISO 15189:2022 for Medical Laboratories-Requirements for Quality and Competence.". The book is designed to be used as a handbook and consists of 22 chapters. The reader will be able to define the process framework of a medical laboratory and identify its documents according to the document hierarchy. Additionally, they can structure the total testing process, which includes preanalytical, analytical, and postanalytical processes both inside and outside the laboratory. Furthermore, the book covers topics on management and support processes as well as data analysis, the development of training programs for laboratory professionals and providing the useful information to the patients. Moreover, the book reviews the governance system, the
alignment of process objectives with strategic goals, outcomes of performed projects related to the medical laboratory management, and the essential competencies for a medical laboratory manager.
This book should be read with the book “Process-Based Management Are You Ready for Digital Transformation? (For Public, Private and Non-Governmental Organizations) by Diler Aslan”